Start Time, How to Watch Thursday Night Football & Who Is Favored

Josh Allen and the Buffalo Bills are taking on the Detroit Lions tonight!

The two teams will face off on Thursday Night Football on Thursday (September 17) at the new Highmark Stadium in Orchard Park, New York.

The game marks the start of the 2026 Thursday Night Football schedule and will also be the Bills’ first regular-season game at the new Highmark Stadium.

Both teams are entering the game with 1-0 records. The Bills defeated the Houston Texans 36-31 in Week 1, while the Lions beat the New Orleans Saints 31-30.

So, what time does the Lions vs. Bills game start tonight and how can you watch it?

What time does the Lions vs. Bills game start?

The Detroit Lions vs. Buffalo Bills game kicks off at 8:15 p.m. ET / 5:15 p.m. PT on Thursday (September 17).

The game is taking place at the new Highmark Stadium in Orchard Park, N.Y.

How to watch Lions vs. Bills tonight

The game will stream nationally on Prime Video as part of Thursday Night Football. It will also be available through NFL+.

Prime Video’s Thursday Night Football coverage begins with a pregame show ahead of kickoff.

Why is tonight’s Lions vs. Bills game special?

Tonight’s matchup will be the first regular-season NFL game played at the new Highmark Stadium, which replaces the Bills’ longtime former home nearby.

The primetime matchup features Bills quarterback Josh Allen facing Lions quarterback Jared Goff, along with stars including James Cook, DJ Moore, Jahmyr Gibbs, Amon-Ra St. Brown and Jameson Williams.

The game also officially kicks off Prime Video’s Thursday Night Football schedule for the 2026 NFL season, which is now in Week 2.

Who will win the Lions vs. Bills game?

According to Kalshi trading as of Thursday morning, traders are giving the Bills a 68% chance of winning, compared to 32% for the Lions.

Josh Allen just opened up his life with his wife, Hailee Steinfeld, and their newborn daughter, Harper.

Posted To:Buffalo Bills Detroit Lions Football Jared Goff Josh Allen nfl Sports